Content about Medicinal chemistry

November 5, 2012

The Food and Drug Administration has approved a drug made by Johnson & Johnson for treating internal blood clots, the company said.

RARITAN, N.J. — The Food and Drug Administration has approved a drug made by Johnson & Johnson for treating internal blood clots, the company said.

J&J subsidiary Janssen Pharmaceuticals announced the approval of Xarelto (rivaroxaban) for treating deep-vein thrombosis and pulmonary embolism and to reduce the risk of recurrence of the clotting conditions after initial treatment.

The company said Xarelto was the first oral anticoagulant approved to treat DVT and PE without the need for injections or routine blood-monitoring.

November 5, 2012

Rx Response, an initiative of America’s bio-pharmaceutical supply system to help ensure the continued flow of medicine to patients in a severe public health emergency, has continued its close coordination with federal, state and local government agencies to address impacts from Hurricane Sandy on the bio-pharmaceutical supply system, the organization announced Friday.

WASHINGTON — Rx Response, an initiative of America’s bio-pharmaceutical supply system to help ensure the continued flow of medicine to patients in a severe public health emergency, has continued its close coordination with federal, state and local government agencies to address impacts from Hurricane Sandy on the bio-pharmaceutical supply system, the organization announced Friday. 

November 5, 2012

The ink was barely dry when we received this response to our Oct. 15, 2012, cover story, “Building the ACO.”


The ink was barely dry when we received this response to our Oct. 15, 2012, cover story, “Building the ACO.”


Dear Editor,


October 29, 2012

Rite Aid is stocking extra emergency supplies and keeping its pharmacies open as Hurricane Sandy bears down on the East Coast, the retail pharmacy chain said.

CAMP HILL, Pa. – Rite Aid is stocking extra emergency supplies and keeping its pharmacies open as Hurricane Sandy bears down on the East Coast, the retail pharmacy chain said.

The company said that stores in the potential path of the storm had increased supplies of bottled water, flashlights, batteries, canned food for people and pets, first aid supplies, disposable cameras, duct tape and cleaning supplies.

October 25, 2012

The Food and Drug Administration has declined to approve a drug developed by United Therapeutics Corp. for treating a potentially lethal high blood pressure condition.

SILVER SPRING, Md. — The Food and Drug Administration has declined to approve a drug developed by United Therapeutics Corp. for treating a potentially lethal high blood pressure condition.

The drug maker said it received a complete response letter from the agency for its application for a tablet formulation of the drug treprostinil. The company already markets the drug in injectable and inhaled formulations for pulmonary arterial hypertension, or PAH, a condition that causes high blood pressure in the arteries of the lungs.

October 19, 2012

The Food and Drug Administration has given tentative approval to a new drug for HIV made by an Indian company.

SILVER SPRING, Md. — The Food and Drug Administration has given tentative approval to a new drug for HIV made by an Indian company.

FDA records show that the agency gave tentative approval tablets and oral suspension that combine lamivudine, nevirapine and zidovudine in the 30-mg/50-mg/60-mg strength.

October 19, 2012

WellTransitions could be couched as another way in which Walgreens is striving to create solutions that lower the cost of overall health care outside of the physical retail pharmacy space, because it is. WellTransitions also could be characterized as a program that will routinely chip away at the $25 billion associated with hospital re-admissions by having more prescriptions filled at the pharmacy counter, because it does. But the real impact of this news? The real clincher? Hospitals need retail pharmacy if they're going to focus on reducing re-admissions, eliminating unnecessary healthcare costs and avoiding those penalties.

And that's the direction Walgreens is headed. Most recently, the company added managed care vet Brad Fluegel as chief strategy officer, adding another talented expert to Walgreens chief Greg Wasson’s dream team, which he has described as the “perfect blend of internal, long-term talent” and “external expertise and talents” that is helping to accelerate a massive transformation in its business. (For exclusive coverage of all Walgreens' efforts, click here for the Sept. 24 DSN special report.)

WHAT IT MEANS AND WHY IT'S IMPORTANT — WellTransitions could be couched as another way in which Walgreens is striving to create solutions that lower the cost of overall health care outside of the physical retail pharmacy space, because it is. WellTransitions also could be characterized as a program that will routinely chip away at the $25 billion associated with hospital re-admissions by having more prescriptions filled at the pharmacy counter, because it does. But the real impact of this news? The real clincher?

October 16, 2012

Emerging multidisciplinary healthcare models, such as accountable care organizations and patient-centered medical homes, promise to elevate quality and lower costs by harnessing the power of provider, payer and patient collaboration. Often overlooked in the coordinated care equation, however, is the integral role pharmacists can play in delivering efficient and effective care.

Emerging multidisciplinary healthcare models, such as accountable care organizations and patient-centered medical homes, promise to elevate quality and lower costs by harnessing the power of provider, payer and patient collaboration. Often overlooked in the coordinated care equation, however, is the integral role pharmacists can play in delivering efficient and effective care.

October 15, 2012

The Food and Drug Administration may be willing to speed up trials for drugs that could be a big benefit to society despite their risks.

SILVER SPRING, M.D. — The Food and Drug Administration may be willing to speed up trials for drugs that could be a big benefit to society despite their risks.

According to several published reports, FDA commissioner Margaret Hamburg recently told a group of scientific advisers that the agency is considering allowing makers of drugs having a societal benefit to conduct faster clinical trials with a smaller group of patients than is now required.

October 15, 2012

Oh, Canada. In some ways, you’re showing your much bigger neighbor in the south the way forward in taking pharmacy to a higher level of practice. And if we’re smart, we’ll pay attention to the results.

Oh, Canada. In some ways, you’re showing your much bigger neighbor in the south the way forward in taking pharmacy to a higher level of practice. And if we’re smart, we’ll pay attention to the results. I’m talking about last week’s announcement by the provincial government of Ontario to expand the role of pharmacists so they can offer services that were previously the exclusive turf of the province’s 25,000 doctors.

October 12, 2012

When given a choice, patients prefer to receive an electronic prescription if they receive a prescription from their physician, according to the most recent Patient Views infographic. To be specific, 64% of respondents said they would choose an e-prescription when provided an option, according to an exclusive survey of nearly 800 patients conducted by AccentHealth and DSN in late July and early August. How many patients are actually given a choice as to how they receive their prescription, and how many currently are receiving electronic prescriptions?

When given a choice, patients prefer to receive an electronic prescription if they receive a prescription from their physician, according to the most recent Patient Views infographic. To be specific, 64% of respondents said they would choose an e-prescription when provided an option, according to an exclusive survey of nearly 800 patients conducted by AccentHealth and DSN in late July and early August. How many patients are actually given a choice as to how they receive their prescription, and how many currently are receiving electronic prescriptions?

October 12, 2012

The Food and Drug Administration has approved an injected drug for lung cancer made by Celgene, the company said Friday.

SUMMIT, N.J. — The Food and Drug Administration has approved an injected drug for lung cancer made by Celgene, the company said Friday.

Celgene announced the approval of Abraxane (paclitaxel) protein-bound particles for injectable suspension, for the first-line treatment of non-small cell lung cancer that has advanced locally or spread to other parts of the body, in combination with carboplatin, for patients who are not candidates for curative surgery or radiation therapy.

October 12, 2012

The Food and Drug Administration has approved a drug made by Sandoz for treating symptoms of various skin diseases.

PRINCETON, N.J. — The Food and Drug Administration has approved a drug made by Sandoz for treating symptoms of various skin diseases.

Sandoz, the generics arm of Swiss drug maker Novartis, announced the approval of desoximetasone ointment in the 0.25% strength. The drug is a generic version of Taro Pharmaceutical Industries' Topicort and, according to Sandoz, is the first Fougera dermatology product Sandoz has launched since its $1.5 billion acquisition of the company in May 2012.

October 11, 2012

A company that manufactures simplified packaging designed to increase medication adherence has launched a new website to promote the product.

HUNT VALLEY, Md. — A company that manufactures simplified packaging designed to increase medication adherence has launched a new website to promote the product.

Medicine-On-Time announced the launch of a new website that connects patients to pharmacies that offer the packaging. The launch includes 250 pharmacies around the country, a number that the company expects to grow. The packaging system is geared toward patients taking multiple drugs and uses personalized pill cups labeled with the day, date and time to take them.

October 11, 2012

The National Association of Chain Drug Stores has announced that it will participate in the annual U.S. Senate Health Fair, which will take place on Oct. 11 to 12 in the U.S. Senate Office complex on Capitol Hill in Washington, D.C.

ALEXANDRIA, Va. — The National Association of Chain Drug Stores has announced that it will participate in the annual U.S. Senate Health Fair, which will take place on Oct. 11 to 12 in the U.S. Senate Office complex on Capitol Hill in Washington, D.C.  

The U.S. Senate Health Fair will offer thousands of Senate employees — including Hill staffers, Capitol Hill Police officers and other employees — an opportunity to receive healthcare advice and care, highlighting the essential role community pharmacy plays in the healthcare delivery system.  

October 5, 2012

The National Community Pharmacists Association on Thursday commended a bipartisan group of 13 U.S. representatives for a letter they jointly sent to the Drug Enforcement Administration requesting “clarification, guidance and collaboration,” and suggesting that the federal agency’s efforts in addressing supply chain issues of controlled substances across Florida-based distribution centers and pharmacies may be inadvertently preventing patients from accessing certain prescription drugs for which they have legitimate medical needs and prescriptions.

ALEXANDRIA, Va. — The National Community Pharmacists Association on Thursday commended a bipartisan group of 13 U.S.

October 2, 2012

Two companies have signed a deal to provide access to real-time medication history to healthcare providers.

NASHVILLE, Tenn. — Two companies have signed a deal to provide access to real-time medication history to healthcare providers.

Pharmacy management services provider PDX and healthcare revenue and payment cycle management and clinical information exchange services provider Emdeon announced the deal Monday, whereby medication history will be delivered from PDX's Electronic Pharmacy Record to Emdeon's Clinical Exchange and then to hospitals, providers, health information exchanges, nursing facilities and ambulatory and acute inpatient facilities that request it.

October 1, 2012

The Council for Responsible Nutrition on Monday announced Jim Griffiths has been named as the association’s VP scientific and international affairs, effective Oct. 10.

WASHINGTON — The Council for Responsible Nutrition on Monday announced Jim Griffiths has been named as the association’s VP scientific and international affairs, effective Oct. 10.

October 1, 2012

Customers who nominate their favorite members of a pharmacy team at local Rite Aid stores will have a chance to win $2,500 in gift cards, the retail pharmacy chain said Monday.

CAMP HILL, Pa. — Customers who nominate their favorite members of a pharmacy team at local Rite Aid stores will have a chance to win $2,500 in gift cards, the retail pharmacy chain said Monday.

September 27, 2012

The Food and Drug Administration has approved a new drug for colorectal cancer developed by Bayer HealthCare.

SAN FRANCISCO — The Food and Drug Administration has approved a new drug for colorectal cancer developed by Bayer HealthCare.

Bayer and Onyx Pharmaceuticals announced the approval of Stivarga for colorectal cancer that has spread to other parts of the body, also known as metastatic CRC, specifically for those patients who have received treatment with currently available therapies.

Bayer developed the drug and will pay royalties to Onyx on future global net sales of the drug for cancer. The two companies will promote the drug together in the United States.

September 27, 2012

With less than six weeks until Election Day, the National Association of Chain Drug Stores grassroots advocacy program is in high gear with its NACDS RxImpact Votes program, urging pharmacy advocates to help shape pharmacy’s future through political engagement.

ALEXANDRIA, Va. — With less than six weeks until Election Day, the National Association of Chain Drug Stores grassroots advocacy program is in high gear with its NACDS RxImpact Votes program, urging pharmacy advocates to help shape pharmacy’s future through political engagement.

The nonpartisan NACDS RxImpact Votes program empowers pharmacy advocates with a toolkit of resources to show the role they can play in the election process. The program focuses its “get out the vote” campaign in three ways:

September 27, 2012

Satisfaction among customers using mail-order pharmacies to fill their prescriptions continued to decline, falling significantly below customer satisfaction with brick-and-mortar pharmacies, according to the J.D. Power and Associates "2012 U.S. Pharmacy Study" released Thursday.

WESTLAKE VILLAGE, Calif. — Satisfaction among customers using mail-order pharmacies to fill their prescriptions continued to decline, falling significantly below customer satisfaction with brick-and-mortar pharmacies, according to the J.D. Power and Associates "2012 U.S. Pharmacy Study" released Thursday.

September 26, 2012

Cardinal Health this week announced that it is kicking off an effort to encourage its retail pharmacy customers to educate their patients about new Medicare benefits and options that will be available under the Patient Protection and Affordable Care Act starting in 2013.

DUBLIN, Ohio — Cardinal Health this week announced that it is kicking off an effort to encourage its retail pharmacy customers to educate their patients about new Medicare benefits and options that will be available under the Patient Protection and Affordable Care Act starting in 2013.

September 25, 2012

Patients diagnosed with serious disease have enough on their minds. So Walgreens is doing all it can to make it easier for them to obtain, administer and pay for their specialty and infused medicines, said Mike Ellis, VP specialty pharmacy and infusion.


Patients diagnosed with serious disease have enough on their minds. So Walgreens is doing all it can to make it easier for them to obtain, administer and pay for their specialty and infused medicines, said Mike Ellis, VP specialty pharmacy and infusion.


“The concept is to go where patients are diagnosed and where they reside. We have a large sales force who call on physicians who prescribe these types of medications. But like everything else at Walgreens, it starts with the patient.”


September 25, 2012

A vast army of some 70,000 Walgreens pharmacists, technicians, nurses and nurse practitioners, and other clinicians is poised to plug some of the gaps in the nation’s overstretched healthcare system with expanded services, greater access for patients and new solutions for providers and payers in desperate need of quality, cost-effective solutions.


A vast army of some 70,000 Walgreens pharmacists, technicians, nurses and nurse practitioners, and other clinicians is poised to plug some of the gaps in the nation’s overstretched healthcare system with expanded services, greater access for patients and new solutions for providers and payers in desperate need of quality, cost-effective solutions.